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Are Fruit Flies Man Enough?

Researchers at Brown University have found that male fruit flies can express a protein that lets them upregulate their X chromosome in order to compensate for "genetic shortcomings," reports LiveScience's Jennifer Welsh. In order for male Drosophila to survive, the researchers write in their study published in Nature, they have to regulate the imbalance created by having only one X chromosome, and they do it by expressing the male-specific lethal protein which doubles the gene expression on the X chromosome, Welsh says. "The finding, if it holds up in humans, could help scientists understand the basis of some X chromosome-linked diseases, which are much more frequent in men because they only have one copy of each X chromosome gene," she adds.

The Scan

Booster for At-Risk

The New York Times reports that the US Food and Drug Administration has authorized a third dose of the Pfizer-BioNTech SARS-CoV-2 vaccine for people 65 and older or at increased risk.

Preprints OK to Mention Again

Nature News reports the Australian Research Council has changed its new policy and now allows preprints to be cited in grant applications.

Hundreds of Millions More to Share

The US plans to purchase and donate 500 million additional SARS-CoV-2 vaccine doses, according to the Washington Post.

Nature Papers Examine Molecular Program Differences Influencing Neural Cells, Population History of Polynesia

In Nature this week: changes in molecular program during embryonic development leads to different neural cell types, and more.