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Approaching Critical Mass?

Looks like people are already warming up for tomorrow's Open Access Day. In the Guardian, Richard Smith pens a column on Springer's acquisition of BioMed Central, which he says may turn out to be a pivotal moment in the history of scientific publishing. "I'm no seer, but it became obvious to me in the mid-90s, when ... I was the chief executive of the BMJ Publishing Group, that the transition to open access would have to happen," he writes. "Once all of science is open access – as it surely will be eventually – then the value of our scientific deposits may be greatly increased." He says that traditional publishers "subtract value by Balkanising the research."

In other open access events, Peter Suber reports that "Google and a group of publishers may be close to settling the publishers' lawsuit against the Google Library Project," the company's initiative of scanning books on library shelves and making them accessible online.

 

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.