Answers and Questions

Whole-exome and whole-genome sequencing raise a number of possibilities, but also questions for use in the clinic. While neither technique is yet a routine diagnostic tool, Jeantine Lunshof from VU University writes in Personalized Medicine that emergencies can speed the introduction of new techniques into medical care, but that there are a number of ethical issue to consider, particularly when the patient is a child.

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The US National Institutes of Health and the Food and Drug Administration have proposed changing gene therapy oversight, the Associated Press reports.

Nature News reports that the Salk Institute has asked for the scope of a gender discrimination lawsuit brought against it to be narrowed.

CNBC reports that the sequencing startup Veritas aims to sequence individuals who fall at extremes.

In PLOS this week: genotyping of indigenous North African goats, program to simulate evolve and resequencing studies, and more.