Dietrich Stephan, of Navigenics and TGen fame, is planning a personalized medicine research institute, reports the Baltimore Business Journal. The $245 million institute will house approximately 500 scientists. Stephan is seeking funding from federal, state, and local levels as well as from universities, nonprofits, and charities, says the Journal.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.