Via Wired, David Ewing Duncan writes for Portfolio.com about the direct-to-consumer personal genetics market, and how this has caught regulatory bodies and health care providers off guard. With the passage of GINA and an advisory committee at the Department of Health and Human Services advocating for tighter regulation of consumer genetic tests, the vetting has begun. "We welcome responsible regulation," says David Agus, co-founder of Navigenics.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.