At bbgm, Deepak Singh waxes sentimental about his first job at a structural biology company, wondering how far their technology would have gotten in today's Software as a Service (SaaS)-based world. (In case you're wondering, SaaS is another name for ASP, where the application service provider distributes fee-for-service software over the Internet.) He points readers to a new plugin called Zemanta

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.