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And Science Ground to a Halt While Reviews Were Underway

At the Medical Writing, Editing & Grantsmanship blog, this post notes the rising estimates of Challenge Grant applications. "Although the dust has not settled as yet, the NIH has currently accepted more than 18K RC1 applications, with another 11K in the error correction queue," according to the blogger. "CSR expects to engage 10K - 15K reviewers" -- which explains why you've probably gotten more than a few invitations already. As a point of comparison, the MWEG blogger says that "for all of 2008, CSR used 16,000 reviewers." Note to NIH: call it a "jamboree" and you might get better response to those reviewer requests.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.