Blogger Thomas Mailund muses about what he would do if $1,000 genomes were readily available in the next year. Since his focus is on finding disease associations, he says the big difference would come from the ability to detect more variants. "With SNP chips and tagging SNPs, we are looking for high-frequent variants with modest effect," he writes. "With full sequencing, we will be able to look for low frequency variants as well."

 

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