Amy Bishop — the University of Alabama biology professor accused of opening fire on her colleagues and killing three of them in 2010 — has entered a plea of not guilty by reason of mental disease or defect, reports the Nature News blog's Meredith Wadman. The trial is set to begin on March 19, 2012, and the prosecution is seeking the death penalty, she adds.

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In PNAS this week: human T cell editing with CRISPR, retrotransposons acting as insulators, and more.

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