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All the Protein's Proteins

May 14, 2007

To look for proteins interacting with the Huntington's disease protein researchers led by Robert Hughes performed both high throughput yeast two-hybrid screenings and affinity pull-down coupled to mass spectrometry. From these techniques, the scientists report in PLoS Genetics that they found over 200 proteins that may interact with the huntingtin protein and affect the neural toxicity of the disease.

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