All About George

George Church graces the August issue of Wired to discuss his personal genome project. The article follows Church's career, including him sitting in front of a teletype in 1967 and up to the development of the Polonator. The PGP allowed what Church calls his "year of convergence" -- when the different threads of his career, as a geneticist, technologist, and synthetic biologist, wove together. He also sees genomics as a source of inspiration. "We need to inspire our current youth in a way that outer space exploration inspired us in 1960.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.