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Alec Bangham Dies

Hematologist Alec Bangham died, reports the Guardian. He was 88. Bangham was best known for discovering liposomes while he was studying the surface chemistry of blood cells, leading him to be nicknamed "the father of liposomes." He always had a small laboratory of only two or three staff members and constantly received visiting scientists from all over the world. His interests extended to the fusion and stickiness of membranes, blood clotting, anesthetics, and vitamin A intoxication. Bangham closely followed how liposomes could be used to treat disease. "They could be used stealthily, like a Trojan horse, to deliver toxic drugs to their targets, as adjuvants for immunization, and to deliver healthy genes where they were needed," writes Brian Heap in the Guardian.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.