When the psychologist Richard Tremblay began studying children with severe behavioral problems in Montreal in the 1980s he had no idea that his pursuits would lead him down a path toward epigenetics.

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In PNAS this week: human T cell editing with CRISPR, retrotransposons acting as insulators, and more.

The New York Times' George Johnson muses on cancer's roots in multicellularity.

The San Diego Union Tribune wonders whether Medicare is ready for personalized medicine.

Jun Wang, the chief executive of BGI, has stepped down.