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Advantage? Maybe, Maybe Not

In a new Genome Research paper, Pavel Pevzner asks whether read length matters. He and his colleagues use a new tool called EULER-USR to assemble mate-paired short reads. They saw that when the read length exceeds a threshold -- about 35 nucleotides in E. coli -- the efficiency of turning mate-pairs into mate-reads is 100 percent, and the read length does not matter, though they add that larger genomes have higher thresholds. Thus, the researchers say it is uncertain if long reads have an advantage over short reads.


The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.