While the human reference genome is done, it's not quite complete. There are a number of regions of the genome that researchers have had trouble accessing, especially near heterochromatic regions and sequences containing a number of repeats. Researchers led by the Broad Institute's Steven McCarroll turned to using an admixture mapping approach to open up those regions, as they describe in this week's American Journal of Human Genetics.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Related Posts

This Week in Nature

This Week in PLOS

This Week in PLOS

This Week in PLOS

This Week in Science

Differences in DNA methylation could be used to distinguish between DNA samples obtained from identical twins, researchers say.

A retrovirus that's been integrated into the human genome appears to have a role in embryonic development, researchers report.

A report from MIT identifies areas of scientific research where declining research support is hindering needed advances.

In PLOS this week: phylogenetic study of hepatitis E viruses in Swedish moose, recombination sites in the honeybee genome, and more.