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'Molecular Mysteries' of Longevity

Canada's National Post this week examines the work of academic researchers working to solve "the molecular mysteries of the healthy to stave off disease and aging." Achieving this, University of Illinois at Chicago's Stuart Olshansky tells the National Post, "will be more important for public health than the introduction of antibiotics. …This will be the medical breakthrough of the 21st Century when it happens." Albert Einstein College of Medicine's Nir Barzilai adds that longevity is "all genetics. … To be 100 years old, it's strongly genetic."

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.