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Technology Spotlight: Washington University

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Following are select notable biotechnologies available for licensing from Washington University (source: Washington University Office of Technology Management):
 
Tech: Image-guided electrophysiologically determined treatment of atrial fibrillation
 
IP Status: Applied for patent (US patent application No. 20070049816)
 
Lead Inventor: Ralph Damiano
 
Description: Surgical method to treat atrial fibrillation, a condition affecting 2 million Americans. The method uses a patient’s own geometry and electrophysiology to “dramatically” improve surgery success rates.
 

 
Tech: Diagnostic method for sepsis
 
IP Status: US patents issued (US patent No. 6,939,716)
 
Lead Inventor: Jay Heinecke
 
Description: Sepsis test analyzes 3-chloro/bromotyrosine biomarkers to diagnose and measure treatment efficacy for the leading cause of death in the elderly and critically ill – 1,400 patients each day, according to Washington University.
 

 
Tech: Load-independent index of diastolic function
 
IP Status: Applied for patent (not yet published)
 
Lead Inventor: Sandor Kovacs
 
Description: Load-independent index of diastolic function enables direct, non-invasive measurement of heart’s actual functionality as a pump, as opposed to only volume of blood pumped.
 

 
Tech: SXC air filtration system
 
IP Status: US patent issued (US patent No. 6,861,036)
 
Lead Inventor: Pratim Biswas
 
Description: Air filtration system captures bio-particles as small as 5 nm with maximum efficiency and uses specialized titanium dioxide to destroy harmful microbes in the air. The technology could be useful for lab hood filtration systems.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.