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Johns Hopkins, Scripps Research Institute, Competitive Technologies License Biotechnologies

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Licensing institution: Johns Hopkins University
 
Primary inventors: Katharine Whartenby, assistant professor, oncology, JHU; Donald Small, professor, oncology, JHU
 
Licensee: Xanthus Pharmaceuticals, Cambridge, Mass.
 
Technology: Xanthus has taken an exclusive worldwide license to a patent estate for treating immune-related disorders by inhibiting the FLT3 tyrosine kinase. In addition, Xanthus and JHU have initiated a research project to assess novel compounds for FLT3 inhibitory activity and the downstream pathways relevant to a range of automimmune diseases.
 

 
Licensing institution: Scripps Research Institute
 
Primary inventor: Joel Gottesfeld, professor, molecular biology, Scripps Research Institute
 
Licensee: Repligen, Waltham, Mass.
 
Technology: Repligen has taken an exclusive worldwide license to IP covering compounds that may have utility in Friedreich’s ataxia, an inherited neurodegenerative disease in which low levels of the protein frataxin result in progressive damage to the nervous system and loss of muscle function.
 

 
Licensing institution: Competitive Technologies
 
Primary inventor: Harley Rotbart, professor, pediatrics and microbiology, University of Colorado Health Sciences Center
 
Licensee: Focus Diagnostics, Cypress, Calif.
 
Technology: Focus Diagnostics will be producing enterovirus assay kits under a recently expanded license granted to it for use of patented technology for the rapid assay of human enteroviruses. The technology was developed by Harley Rothbart at UC, a Competitive Technologies client.

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