Visiting the nation's top life-sciences cluster as part of a four-day, three-state West Coast trade trip, Massachusetts' top life-sci official last week joined the state's governor and other state leaders in rolling out a campaign to recruit bioscience and other tech businesses to the Bay State.

One pitch: Contrasting Massachusetts' $1 billion, 10-year life-sci initiative with California's general budget woes.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.