Officials in Cambridge, Mass., last week began reviewing a request by real estate developer Beal Companies to rezone land north of its One Kendall Square mixed-use complex into a separate project that would feature more laboratory and other commercial uses, and less residential space, than the city currently allows.

The proposal seeks to enable Beal "to target both" smaller and larger potential users for the lab space, Peter Spellios, senior vice president and general counsel for the company, told BioRegion News last week.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.