Autoimmune Disease
News on research and diagnostics in autoimmune disorders including rheumatoid arthritis, lupus, multiple sclerosis, and more.
Gene Expression, Histology Reveal Clues for Targeted Rheumatoid Arthritis Treatment
Histological profiling and RNA sequencing helped identify synovial biopsy features for predicting targeted biologic therapy response in rheumatoid arthritis.
The Seattle-based company recently completed a strategic reorganization around its two major business areas by cutting the workforce and appointing a new CFO.
Lupus Linked to TLR7 Mutations, Related Signaling Changes
Gain-of-function mutations in TLR7 were found to cause systemic lupus erythematosus through excess TLR7 pathway activation, pointing to possible treatment targets.
Single-Cell Sequencing Study Uncovers Blood Cell Type-Specific Features
Single-cell RNA sequencing and other approaches helped characterize systemic lupus erythematosus immune features, including cell type-specific expression profiles.
The Seattle-based company recently published immune repertoire data showing the potential of T-cell receptor profiling in IBD diagnostics.