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Yokogawa Electric, Samsung Electronics, THK, Corning, NGK Insulators

Yokogawa Electric of Tokyo has received European Patent No. 1767926, "Biochip reading apparatus and biochip reading method." The patent describes a biochip analysis method based on distribution of the light quantity of fluorescence generated at a site on a biochip. According to the patent's abstract, a site position on an array can be detected using transmitted light or reflected light. When reflected light is used, a light source is activated. Light passes through a barrier filter and is bent by a dichroic mirror. The light passes through the mirror and illuminates the biochip. The reflected light from the biochip then enters a CCD camera, and an output signal is sent to a computational system, which detects the position of a site on the biochip.
Yokogawa Electric has also received European Patent No. 1767925, "Biochip and analytical instrument for analyzing same." The patent claims a biochip containing a number of probe sites bound to a known number of fluorescent molecules. Because the number of molecules bound to the probe sites is known, respective hybridization efficiencies at the probe sites can be quantitatively grasped by comparing the intensity of fluorescent light at the probe sites with the intensity of the fluorescent light at the marker sites, the patent claims.

Samsung Electronics of Gyeonggi-Do, Korea, has received European Patent No. 1767368, "Spitting Method of an Array-type Inkjet Image Forming Apparatus." The patent claims an inkjet arraying method that is capable of minimizing the amount of material consumed during the spitting process. According to the patent, the method works by spitting material several times during the microarraying process in order to optimize the condition of the printhead.

THK of Tokyo has received US Patent No. 7,198,758, “Microarraying head and microarrayer.” The patent describes a microarraying head and a microarrayer where the work of forming spots and the work of cleansing and drying the microarraying head can be carried out simultaneously so that microarrays can be produced efficiently. The patent claims a microarraying head with a base portion and a plurality of needles. The needles place a solution on substrates with the top ends of the needles touching the substrates. Then, the needles retain the solution including biological samples and form spots of the solution on the substrates. A space for supplying cleansing fluid is also present in the base portion. Since the needles can be all cleansed under uniform pressure, all the
needles can be cleansed in a short time, the patent states.

Corninghas received US Patent No. 7,198,768, “Anti-degradation mechanisms for protecting aminated surfaces.” The patent claims a device and methods for either protecting or restoring the surface chemistry of amine-coated substrates adapted for biological assay. Degradation often results from exposure to carbon dioxide and/or organic chemical compounds, which may arise in packaging or storage containers, the patent states. The device encompasses an enclosure, preferably hermetically sealed, a component susceptible to degradation from either carbon dioxide or organic compounds, and a sorbent, having a composition made from either a single material or a combination of materials. The sorbent is characterized as being reactive with CO and has high-surface energy for removing organic compounds. The method can stabilize the surface chemistry and prolong the useful life of the coated substrate.

NGK Insulators of Nagoya, Japan, has received US Patent No. 7,200,254, “Probe reactive chip, sample analysis apparatus, and method thereof.” The patent describes an automated execution method for the alignment of a detection area to a DNA microarray image file and a process for quantitative determination of success or failure of the alignment during DNA microarray analysis.

The Scan

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Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.