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X-Miner On-Line


X-Mine of Brisbane, Calif., has unveiled its Opus biological knowledge discovery application, a text mining program designed to allow researchers to extract literature-based biological relationships between genes without performing an exhaustive literature search. The program presents the results in a table that displays relationships between genes and scores indicating the strength of the relationship. This product introduction comes just after the company introduced its X-Miner On-Line genomic analysis system, an online microarray data mining package, which includes clustering algorithms, supervised machine learning programs, and also uses its “Reporter” engine to mine biological literature and genome databases in order to find biologically meaningful relationships.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.