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Whatman, GE Healthcare, VigeneTech, Epicentre Biotechnologies, Affymetrix, London Genetics

Whatman, part of GE Healthcare, and VigeneTech last week announced the launch of custom software to analyze Whatman FAST Quant samples. The customized original-equipment-manufactured software from VigeneTech provides high-quality image quantification and enhances the automation for Whatman FAST Quant protein array image and data analysis, the companies said.
A customized version of MicroVigene from VigeneTech now enables FAST Quant users to analyze fluorescent immunoassay results from multiplexed platforms. More accurate spot finding in an array format assures increased accuracy of assay results, the duo said.

Epicentre Biotechnologies this week launched its TargetAmp 1-Round Biotin-aRNA Amplification Kit 105, which produces biotin-aRNA from as little as 25 nanograms of total RNA, the company claims.
The labeled RNA yields high-quality results on Affymetrix GeneChip arrays as judged by signal intensity and present calls, Epicentre said.

London Genetics this week launched its molecular cytogenetics testing service. The new service covers all aspects of molecular and conventional cytogenetics.
According to the firm, the service can already provide techniques such as array comparative genome hybridization, copy number variation validation, G-banding, and fluorescence in situ hybridization analyses.

The Scan

Expanded Genetic Testing Uncovers Hereditary Cancer Risk in Significant Subset of Cancer Patients

In Genome Medicine, researchers found pathogenic or likely pathogenic hereditary cancer risk variants in close to 17 percent of the 17,523 patients profiled with expanded germline genetic testing.

Mitochondrial Replacement Therapy Embryos Appear Largely Normal in Single-Cell 'Omics Analyses

Embryos produced with spindle transfer-based mitochondrial replacement had delayed demethylation, but typical aneuploidy and transcriptome features in a PLOS Biology study.

Cancer Patients Report Quality of Life Benefits for Immune Checkpoint Inhibitors

Immune checkpoint inhibitor immunotherapy was linked in JAMA Network Open to enhanced quality of life compared to other treatment types in cancer patients.

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.