• Linear amplification patents by Russell Van Gelder, James Eberwine, and others. These include not only the patents at issue in the Incyte-Affymetrix litigation, US Patent Numbers 5,716,785 and 5,891,636, but also US Patent Number 5,545, 522, “Process for amplifying a target polynucleotide sequence using a single-primer promoter complex.” These patents cover the popular T7 Eberwine protocol for linear amplification, and has already been licensed to Merck among others.


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