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University of California, NuGen Technologies, Bureau of Animal and Plant Health Inspection and Quarantine, Electronics and Telecommunications Research Institute

The University of California of Oakland has received US Patent No.7,402,286, “Capillary pins for high-efficiency microarray printing device.” The patent provides a microarray print head that includes glass or quartz-spotting capillaries in a support. A fixed spacing between the spotting capillaries is maintained that permits the spotting capillaries to move in a direction parallel to the long axis of the capillaries.

NuGen Technologies of San Carlos, Calif., has received US Patent No. 7,402,386, “Global amplification using random priming by a composite primer.” The patent discloses methods, compositions, and kits for global amplification. The methods provide for amplification using a composite primer that is capable of binding to multiple sites within template polynucleotides, where a large multiplicity of template polynucleotide sequences is amplified. The methods are suitable for use with either DNA or RNA template and generate polynucleotide products that are suitable for a variety of uses including comparative genome hybridization, expression profiling, and multiple genotype determinations, for example, by multiplex analysis by microarray technologies.

The Bureau of Animal and Plant Health Inspection and Quarantine of Taipei, Taiwan, has received US Patent No. 7,402,411, “Species-specific probes for identification of target virus and identification method using said probes.” The patent provides a method for identifying a target virus in an infected subject by: a) designing a pair of degenerate primers corresponding to highly conserved regions of the target virus; b) designing a pair of species-specific primers according to highly variable sequences within the conserved regions of the target virus; c) preparing the species-specific probes according to the larger sequence variations within the conserved regions of the target virus, which are amplified with the species-specific primers as obtained; d) preparing a test sample by amplifying total nucleic acid of the infected subject with the degenerate primers as obtained; contacting the test sample with the species-specific probes as obtained; and e) detecting a hybridization between the species-specific probe and the test sample, where the hybridization indicates the target virus is identified in the infected subject.

Electronics and Telecommunications Research Institute of Daejeaon, Korea, has received US Patent No. 7,403,236, “Programmable mask and method of fabricating biomolecule array using the same.” The patent describes a programmable mask that can be used in a photolithographic process for fabricating a biomolecule array and a method of fabricating a biomolecule array using the same mask.

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more