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The University of California, Berkeley, Packard Instrument, PerkinElmer, FSM Technologies


The University of California, Berkeley, has granted an exclusive license to nascent labeling company Lumiphore for US Patent No. 6,406,297, “Salicylamide-Lanthanide Complexes for Use as Luminescent Markers.” The patent, granted in June, covers fluorescence detection technology using lanthanide complexes. The technology was developed in the lab of UC Berkeley professor Kenneth Raymond, who co-founded Lumiphore along with his then-postdoc Stephane Petoud last year. The company said its technology offers higher signal-to-noise ratios and, consequently, higher sensitivity in comparison to current fluorescence detection systems. It also enables detection of four visible colors and several infrared colors, and resists photobleaching, according to Lumiphore.

Packard Instrument, now absorbed into PerkinElmer, has received US Patent No. 6,465,640, “Apparatus and method for calibration of a microarray scanning system.” The system describes a device that automatically calibrates both the detection system and the radiation source on the scanner through irradiation of the dilution spots, detecting the radiation produced by them, obtaining a series of brightness readings and analyzing the readings to obtain a fluorophore brightness. The detection system or the excitation radiation source is then adjusted to fit the brightness of the fluorophore.

FSM Technologies of Glasgow, UK, has obtained US Patent No. 6,465,640, “Method and device for purifying nucleic acids.” The patent describes methods for purifying nucleic acids from samples of whole cells, including whole blood samples. It also details a filter that is used in this filtration process.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.