Skip to main content
Premium Trial:

Request an Annual Quote

United States of America, Takara Bio, and Syntrix Biochip

Premium

The United States of America of Washington, DC, has received US Patent No. 6,951,761, "Measurements of multiple molecules using a CryoArray." The patent claims CryoArrays that permit the analysis of samples — such as protein, nucleic acid, virus, or cell samples — in arrays that are prepared at low temperatures with minimal amounts of samples. CryoArrays are constructed as a block of columnar samples and can be sliced to provide a plurality of identical or substantially identical individual arrays, the patent claims. Also claimed are methods of making CryoArrays, devices for making CryoArrays, and kits. Methods for constructing classes of CryoArrays are provided, including protein-based CryoArrays, nucleic acid-based CryoArrays, cell-based CryoArrays, delivery CryoArrays, virus-based CryoArrays, and sample-based CryoArrays, are also claimed in the patent.


Takara Bio of Shiga, Japan, has received US Patent No. 6,951,722, "Method for amplifying nucleic acid sequence." The patent claims methods for amplifying a nucleic acid sequence characterized by effecting a DNA synthesis reaction in the presence of chimeric oligonucleotide primers. The methods described are a method for supplying a large amount of DNA amplification fragments; a method for amplifying a nucleic acid sequence by combining the above method with another nucleic acid sequence amplification method; a method for detecting a nucleic acid sequence for detecting or quantitating a microorganism such as a virus, a bacterium, a fungus or a yeast; and a method for detecting a DNA amplification fragment obtained by the above method in situ.


Syntrix Biochip of Auburn, Wash., has received US Patent No. 6,951,682, "Porous coatings bearing ligand arrays and use thereof." The patented invention provides coated articles comprising a substrate having a continuous porous coating of uniform thickness, where the coating comprises a gelled network of particles, and where the porous coating has two or more different compounds attached to it. Suitable particles may comprise one or more of carbon, activated carbon, fluorinated carbon, styrenedivinylbenzene copolymers, polystyrene, zeolites, oxides of antimony and oxides of metals present within Group III and Group IV of the periodic table, the patent claims. The gelled network of particles further comprises a polymer of a partially or substantially hydrolyzed metal alkoxide and substrates include glass and may comprise an adhesive layer. Attachment of compounds to the porous coating may be covalent or via adsorption, with or without the use of a linker. Preferred compounds include nucleobase polymers, peptides, and enalaprilat analogues.

The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.