Tried and True, With a Twist

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Coupling a genome-wide association study with a novel computational method, researchers at the Children's Hospital of Philadelphia identified four genes — DUSP12, DDX4, IL31RA, and HSD17B12 — that harbor variants linked to the development of neuroblastoma, a common childhood cancer. The team, led by CHOP's John Maris, concentrated on the low-risk form of the disease, which has not been as extensively studied as the high-risk form.

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