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Thomas Gerson, Gerald Vardzel, Sam Gambhir, Illumina, CombiMatrix, Iconix Pharmaceuticals, Kreatech Biotechnology, Koada Technology

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Thomas Gerson has been appointed vice president of business operations and chief financial officer at HistoRx, the company said this week.

Prior to joining HistoRx, Gerson served as chief financial officer of CGI Pharmaceuticals, after serving as vice president of finance and operations for CGI. He has also worked for Sanofi Pharmaceuticals, where he was director of financial planning and analysis for Sanofi's research division, and Sterling Winthrop Consumer Health Group, where he served as director of financial planning and analysis.

Gerson holds an MBA in finance from the University of Chicago and a BA in economics and history from Boston College.


Gene Express named Gerald Vardzel CEO last week. He was also appointed assistant to chairman of the board.

Vardzel was previously vice president of business development at the company. Prior to Gene Express, he held several key management positions at Becton Dickinson. He has also been a consultant for small- to mid-size equity firms. He is a director for JKMP Group.


Sam Gambhir has become a director at Lumera, the company said last week.

Gambhir is a professor in the nuclear medicine division at Stanford University School of Medicine and is the director of the school's molecular imaging program.

 

New Product Watch

Illumina this week announced the availability of three GoldenGate SNP assay panels designed to study genetic variation and help researchers understand how certain genotypes impact disease.

Specifically, Illumina launched its GoldenGate Cancer Panel, which the company claims can genotype 1,421 loci on over 400 genes thought to be related to disease progression. It has also released two GoldenGate Mouse Linkage Mapping Panels for GoldenGate genotyping. According to Illumina, the first panel includes 377 validated SNP loci optimized for the 10 most common inbred mouse strains used in genetic mapping, while the second panel includes 1,449 loci, and can provide higher resolution and broader mapping capability.

Additionally, Illumina has introduced Sentrix universal arrays that contain a multiplex level of 96 GoldenGate assays. Illumina said the enhancement will enable users to genotype sets of custom markers ranging from 96 to 1,536 SNPs per array.

Also, Illumina has launched a GoldenGate DNA Test Panel composed of more than 360 markers that reside outside of genes and conserved sequences and are likely to be neutral to disease association. The company said the panel can be used to selectively pre-screen sample DNA quality prior to embarking on a large-scale genotyping study.


CombiMatrix this week launched its ElectraSense Influenza Typing System, the company said.

CombiMatrix said that the ElectraSense System is a portable system that uses the company's Influenza A Typing Microarray and enables users to verify whether samples contain a highly pathogenic substrain of H5N1 or one of the several non-lethal substrains of H5N1.

The company said that it is prepared to make this system available to domestic and international government agencies that are engaged in monitoring influenza and planning for a potential pandemic. The system is designed for research use, surveillance and monitoring applications, animal studies, and other applications not requiring US Food and Drug Administration registration. CombiMatrix will seek FDA approval for this product, the company said.


Iconix Pharmaceuticals said this week that it has added data generated with the Affymetrix microarray platform to its DrugMatrix toxicogenomic database.

According to Iconix, the DrugMatrix expansion adds data for hundreds of compound treatments in liver, kidney, heart and cultured primary rat hepatocytes. The database now includes data generated by the Affymetrix GeneChip RG-230 2.0 Array, which interrogates more than 30,000 transcripts and variants from the rat genome, including more than 28,000 rat genes.


Kreatech Biotechnology has launched its single-color ULS Protein Labeling and Fluorescent Detection Kits for proteomics applications, the company said.

The kits are intended to profile of serum and cell lysate samples on high-content antibody arrays and are an addition to the company's two-color protein labeling kits for profiling on antibody arrays, Kreatech said.

The kits offer Kreatech's universal linkage system labeling molecule bound to biotin or fluorescein for direct labeling of protein analytes in serum and cell lysate samples, and include blocking and washing buffers and Kreatech's ULS Trap purification column.


Koada Technology this week released Koadarray V2.6, its software for automated microarray image analysis and quantification.

According to Koada, Koadarray V2.6 contains a number of improvements, including improved spot-finding algorithms and the ability to output data in a GenePix-compatible format.