As new studies continue to elucidate the link between structural variants and disease, these variants are increasingly associated with multiple distinct diseases, complicating their diagnostic utility. For example, a recurrent deletion on chromosome 15q13.3 has been associated with intellectual disability, schizophrenia, autism, and idiopathic generalized epilepsy, while another deletion on chromosome 16p11.2 has been associated with intellectual disability, obesity, schizophrenia, and sporadic cases of autism.

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In Genome Research this week: mitochondrial and nuclear gene fusions in cancer, role of genomic imprinting in tissue-specific gene expression, and more.

Maria Freire from the Foundation for the NIH calls for "politically popular pledges of support" for the NIH to turn into support for increased funding for the agency.

A Thomson Reuters analysis indicates that the life sciences, rather than the tech sector, are increasingly driving global innovation.

The White House says ethical discussions about genome editing of the human germline are needed.