Team Proposes 'Multiple-Site Model' for Interpreting Variants Associated with Multiple Disorders | GenomeWeb

As new studies continue to elucidate the link between structural variants and disease, these variants are increasingly associated with multiple distinct diseases, complicating their diagnostic utility. For example, a recurrent deletion on chromosome 15q13.3 has been associated with intellectual disability, schizophrenia, autism, and idiopathic generalized epilepsy, while another deletion on chromosome 16p11.2 has been associated with intellectual disability, obesity, schizophrenia, and sporadic cases of autism.

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In PNAS this week: chromosome instability in S. cerevisiae, structural differences and sequence divergence in rice, and more.

The San Diego Union-Tribune takes a look at the work to be done in personalized medicine.

An op-ed in the Wall Street Journal calls for the establishment of a patent court staffed by judges and experts with science backgrounds.

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