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Stratagene, Affymetrix, Imaging Research, Amersham Biosciences, Affibody, InforSense, AutoGen


Stratagene has agreed to exclusively distribute and co-market four of Iobion Informatics’ desktop informatics packages — GeneSolve, ProteinSolve, PathwayAssist, and ArrayAssist — the La Jolla, Calif.-based sister companies said last week. The packages will be sold individually, as well as in a suite named IobionLab. PathwayAssist package uses a natural language processor to use the literature to build biological association networks. GeneSolve and ProteinSolve include capabilities for importing, visualizing, and interpreting DNA and protein sequence information. ArrayAssist is designed for impor-tation and analysis of Affymetrix microarray data.


Imaging Research of St. Catharines, Ontario, a subsidiary of Amersham Biosciences, announced the release of ArrayVision v8.0 last week for analysis of genomic and proteomic arrays. New features include a new GUI, background subtraction options for protein arrays, new weighting functions for improved curve-fitting, flexible graphing tools and simplified import/export functions.


Affibody of Stockholm, Sweden, and InforSense of London last week released KDE GeneSense — an application for interpreting experimental genomics, transcriptomics, and proteomics data with available scientific knowledge for the identification and validation of potential drug targets. GeneSense couples InforSense’s Kensington Discovery Edition informatics with Affibody’s data management, biological annotation (ontology) and visual representation technology.


AutoGen is introducing AugGenPrep 240, an automated robotic system for isolating DNA from bacterial samples. The benchtop instrument can process up to 24 samples in three hours and will be available June 1.


The Scan

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.

Coronary Artery Disease Risk Loci, Candidate Genes Identified in GWAS Meta-Analysis

A GWAS in Nature Genetics of nearly 1.4 million coronary artery disease cases and controls focused in on more than 200 candidate causal genes, including the cell motility-related myosin gene MYO9B.

Multiple Sclerosis Contributors Found in Proteome-Wide Association Study

With a combination of genome-wide association and brain proteome data, researchers in the Annals of Clinical and Translational Neurology tracked down dozens of potential multiple sclerosis risk proteins.

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.