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Steve Lombardi, Stan Lapidus, Bill Efcavitch, Marc Levine, Stan Letovsky

Helicos BioSciences last month appointed president and chief operating officer Steve Lombardi to be its new CEO, while current CEO Stan Lapidus will remain chairman of Helicos’ board of directors.
Lombardi will retain his position as president of the company while taking on the new position, Helicos said. He previously served as vice president of Applied Biosystems’ DNA sequencing and genetic analysis unit, and as senior vice president at Affymetrix.
In addition, Helicos recently named Bill Efcavitch to be chief technology officer, Marc Levine to be senior VP of product development, and Stan Letovsky as VP for scientific informatics.

Efcavitch was promoted from VP of product development, and he previously spent 24 years at Applied Biosystems. Levine previously was involved in commercialization and development of capital equipment at Teradyne. Letovsky spent 20 years working in industrial bioinformatics and had management roles at Codon Devices, Millennium Pharmaceuticals, and Monsanto.

The Scan

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While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.