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SigmaPlot 8.0, Onto-Express


SPSS has released a new version of its SigmaPlot scientific graphing software, SigmaPlot 8.0, that can generate professional graphs from a Microsoft Excel worksheet. It also includes new toolbar palettes that allow users to modify bars, lines, highlight groups or data, and modify numerous items at once. Users can directly edit text on the graph page, and can modify font size, type, color, and alignments. SigmaPlot 8.0 is selling for $699. Upgrades are available for $199 for SigmaPlot 7.1 and 6.0, and $299 for SigmaPlot 5.0 or lower. For users of SigmaPlot 7.1 2001, the update is available for free at


The Wayne State University Department of Computer Science in Detroit has released version 1.5 of Onto-Express, a functional gene expression analysis tool that allows users to input the set of differentially regulated genes in an experiment, and then returns information about the set of biological processes in which these genes are involved.

The new version supports the mouse genome, as well as “dramatic improvements in speed,” said Sorin Draghici, assistant professor of computer science at Wayne State and the Onto-Express creator. “Results for most queries will now be displayed in less than one minute.” The update also includes a button that launches a sample query, in order to demonstrate to new users how Onto-Expresses works. Onto-Express is available for free at:

The Scan

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.

Lupus Heterogeneity Highlighted With Single-Cell Transcriptomes

Using single-cell RNA sequencing, researchers in Nature Communications tracked down immune and non-immune cell differences between discoid lupus erythematosus and systemic lupus erythematosus.

Rare Disease Clues Gleaned From Mobile Element Insertions in Exome Sequences

With an approach called MELT, researchers in the European Journal of Human Genetics uncovered mobile element insertions in exomes from 3,232 individuals with or without developmental or neurological abnormalities.

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.