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Sigma-Aldrich, Global Genomics, Ariadne Genomics, GE Healthcare


Sigma-Aldrich has launched the Panorama Ab Microarray Cell Signalling Kit, the first in a line of antibody-based microarrays the firm plans to introduce. The kit consists of 224 immobilized antibodies and utilizes a specialized format that maintains antibody activity and specificity within a three-dimen-sional structure and nitrocellulose layer.

Global Genomics is preparing to release an improved version of its tangerine gene expression profiling database covering 168,000 human transcripts. The firm’s mouse transcriptome, containing 130,000 transcripts is available now, while the firm’s human and rat transciptomes will be available soon.

Ariadne Genomics has introduced its PathwayAssist 3.0 desktop software for visualization and analysis of biological pathways. The new software includes a database of more than 500,000 molecular interactions for pathway data mining, improved visualization tools, and enhanced gene expression data analysis functionality, the firm said.

GE Healthcare has launched its CodeLink Mouse Whole Genome Bioarray, the third whole-genome array released this year by GE (see BAN 10/20/2004 for more detail).

The Scan

Suicidal Ideation-Linked Loci Identified Using Million Veteran Program Data

Researchers in PLOS Genetics identify risk variants within and across ancestry groups with a genome-wide association study involving veterans with or without a history of suicidal ideation.

Algorithm Teases Out Genetic Ancestry in Individuals at Biobank Scale

Researchers develop an algorithm known as Rye to tease apart ancestry fractions in admixed individuals at a biobank-scale, applying it to 488,221 UK Biobank participants in Nucleic Acids Research.

Multi-Ancestry Analysis Highlights Comparable Common Variants at Complex Trait-Linked Loci

Researchers in Nature Genetics examine common variants implicated in more than three dozen conditions, estimating genetic effect similarities across ancestry tracts in admixed individuals.

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.