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Sequenom, MRC Geneservice, Matsushita, Beijing Genomics Institute, Danish Committee of Pig Breeding and Production

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Sequenom's New CEO to Earn $420K Per Year,
Up to $210K in Performance Bonus

Harry Stylli, Sequenom's newly hired president and CEO, will receive an annual salary of $420,000 and will be eligible for an annual performance bonus of up to 50 percent of that salary.

When he starts his new job on June 6, Stylli will be eligible to purchase 1 million shares of stock at a price per share equal to the fair market value on his start date, Sequenom said in an SEC filing this week.

Stylli will replace Stephen Zaniboni, Sequenom's chief financial officer who has served as acting CEO since February when Toni Schuh stepped down.


After Management Buyout, MRC's Genome Service
Will Continue Commercially as Geneservice

Following a management buyout, MRC Geneservice, a provider of genomics reagents and services funded by the UK's Medical Research Council, will on Aug. 1 re-emerge as a commercial company called Geneservice, Cambridge, UK-based MRC Geneservice said this week.

The new company will take over the assets and most of the staff of government-funded MRC Geneservice and will be based in the Cambridge Science Park.

Geneservice will continue to archive and distribute genomic reagents, such as bacterial clones and human DNA samples generated by academic groups and consortia, and provide genomic services, such as DNA sequencing, genotyping, microarray expression analysis, and genome amplification.

In addition, the company plans to invest in new business opportunities, including resources such as RNAi and protein expression libraries.


Matsushita Develops Array For Use
in Groundwater and Soil Remediation

Japanese firm Matsushita Environmental & Air-Conditioning Engineering this week announced it has developed a microarray to measure the effectiveness of bacteria in decomposing volatile organic compounds.

The array was developed in collaboration with Gifu University and Japan's Human Stress Signal Research Center of the National Institute of Advanced Industrial Science and Technology, and can be used to verify that efforts to purify soil and groundwater using soil microorganisms are working, the company said.

Matsushita anticipates sales in its groundwater and soil remediation business to double from the current 3.5 billion yen ($32 million) to 7 billion yen by 2008.


Chinese, Danish Team Release .66X Coverage
of Pig Genome Sequence

The Chinese Academy of Sciences' Beijing Genomics Institute and the Danish Committee of Pig Breeding and Production have publicly released their pig genome sequence, the partners said last week.

The data are based on 3.84 million shotgun sequences, or .66X coverage, of five different domestic pig breeds from Europe and China, the groups said. The data are generated from the Sino-Danish Pig Genome Project, which began in 2001.

The sequence has been deposited into the NCBI Trace repository under the name "SDJVP."

The researchers aligned the non-repetitive fraction of the sequences to the UCSC human-mouse alignment and annotated the resulting data using the human genome annotation. The results "show that for each of these types of orthologous data, pig is much closer to human than mouse is," the researchers report.

The researchers have also analyzed 100 libraries of expressed sequences from different pig tissues and developmental stages. These sequences will be "released in the near future together with a publication on pig gene expression," the team said in a statement.

The sequencing was paid for with $10 million by CAS, DCPBP, and China's Ministry of Science and Technology Natural Science Foundation.

The research indicates that pig is genetically closer to man than normally used laboratory animals. The finding has "important implications" for the use of pigs in medical research and drug testing.

The Scan

Could Cost Billions

NBC News reports that the new Alzheimer's disease drug from Biogen could cost Medicare in the US billions of dollars.

Not Quite Sent

The Biden Administration likely won't meet its goal of sending 80 million SARS-CoV-2 vaccine doses abroad by the end of the month, according to the Washington Post.

DTC Regulation Proposals

A new report calls on UK policymakers to review direct-to-consumer genetic testing regulations, the Independent reports.

PNAS Papers on Mosquito MicroRNAs, Acute Kidney Injury, Trichothiodystrophy

In PNAS this week: microRNAs involved in Aedes aegypti reproduction, proximal tubule cell response to kidney injury, and more.