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Schizosaccharomyces pombe microarray, OptArray


Eurogentec of Liège, Belgium, has released a Schizosaccharomyces pombe microarray. The array contains PCR products for approximately 99.5 percent of annotated fission yeast genes, including mitochondrial genes, tag, and marker genes, according to the company. It was developed in partnership with an academic consortium headed up by Anthony Wright of Södertörns University College and the Department of Biosciences of the Karolinska Institute in Sweden. Wright’s preliminary analysis shows that the array reliably detects over 75 percent of fission yeast transcripts. Eurogentec also sells Saccharomyces cerevisiae and Candida albicans microarrays.


Prolinx, of Bothell, Wash., has applied its Versalinx protein microarray technology to the creation of peptide arrays. Versalinx utilizes the specific interaction between molecules containing P(D)BA (phenyl(di)boronic acid) and SHA (salicylhydroxamic acid) to link or attach nucleic acids, proteins, and other macromolecules for use in analytical and preparative assays. “Using Versalinx technology, peptides are rapidly and easily modified in solution or during solid phase peptide synthesis, then immobilized on the array surface,” company literature states. Prolinx further claimed that its chemistry produces improved retention of peptide activity, uniform spot morphologies, and results in a linear response over “a wide range of peptide concentrations.”


Accelr8 Technology of Denver, Colo., has made its debut in the protein array market, introducing two different biotin-coated OptArray microarray slides. The slides use the company’s proprietary surface chemistry, which is designed for a maximum signal-to-noise ratio and to minimize non-specific binding. The company plans to introduce amine-reactive and thiol-reactive surfaces for microarray slides before the end of July.


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