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Samsung Electronics, Nanogen, Applera, 3M

Samsung Electronics of Seoul, South Korea, has received European Patent No. 1759759, "Devices and methods for printing biomolecular droplet on substrate and device for printing ink on substrate or print paper using electric charge concentration effect." According to the patent's abstract, the device enables the printing of a biomolecular droplet onto a target surface of the substrate. The device is then able to manufacture a high-density biochip by depositing numerous biomolecular droplets small in size and volume onto the substrate. The device includes a needle-shaped, electric field-forming electrode; a substrate that is disposed below the electric field-forming electrode that is grounded and includes a target surface; and an open circuit type voltage applying unit that supplies first electric charges to the electric field-forming electrode so that the biomolecular droplet drops onto the target surface of the substrate.

Nanogen has received US Patent No. 7,186,813, “Biomolecules having multiple attachment moieties for binding to a substrate surface.” The patent claims biomolecules with multiple binding sites for attachment to a substrate surface. The multiple attachment sites may be produced directly on the biomolecule or through use of branched phosphoramidite moieties that can be added in multiple to form dendritic structures which can in turn provide attachment sites for substrate binding moieties, the patent’s abstract states. Substrate binding moieties may include non-covalent and covalent binding moieties. For covalent binding moieties oligonucleotides containing hydrazides are described.

Applera has received US Patent No. 7,187,286, “Methods and systems for using RFID in biological field.” The patent claims an apparatus for associating information with a biological reagent where the apparatus includes a carrier for supporting the biological reagent. According to the patent, the carrier is a surface plasmon resonance array. Methods are also claimed where a tag comprising a carrier antenna is coupled to the carrier, is read by a reader, and includes licensing rights information for at least one of the carrier and the biological reagent. The licensing rights information is then used to authorize, validate, and authenticate use of the carrier and the biological reagent in a predetermined assay.

3M of St. Paul, Minn., has received US Patent No. 7,189,842, “High density, miniaturized arrays and methods of manufacturing same.” The patent claims high-density, miniaturized arrays including high surface areas. Arrays described include substrates with a coating of linking agents, as well as arrays with reactants affixed to the substrates. Methods of manufacturing high-density arrays of reactants are also claimed. The methods include the use of oriented, heat shrink films and elastomeric materials. Methods of functionalizing a substrate with linking agents for subsequent affixation of reactants are also discussed in the patent.

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