Affymetrix received US Patent No. 6,600,996, “Computer-aided techniques for analyzing biological sequences.” The patent covers computer-aided techniques for ana-lyzing biological sequences such as nucleic acids. The computer system may analyze hybridization intensities indicating hybridization affinity between nucleic acid probes and a sample nucleic acid sequence in order to call bases in the sample sequence. Multiple base calls may be combined to form a single base call.

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