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Roche NimbleGen, Affymetrix

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Roche NimbleGen last week launched a line of eukaryotic 4-plex NimbleChip Multiplex Arrays for human, mouse, rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Arabidopsis thaliana, Caenorhabditis elegans, and Drosophila melanogaster. Researchers can also request custom gene expression arrays in the 4-plex format for any eukaryote with a well annotated genome, the firm said.
 
The multiplex format enables users to hybridize and analyze samples in four replicate arrays on a single slide and makes use of Roche NimbleGen’s 60-mer oligonucleotide probes in combination with high density sub-arrays of 72,000 probes allowing multiple probes per gene.
 

 
Affymetrix this week launched its GeneChip Mouse and Rat Gene 1.0 ST Arrays, the second and third installments of its Gene 1.0 ST Array System.
 
According to Affy, the gene-level arrays use its Whole Transcript Sense Target Labeling Assay and enable users to view a gene's total transcriptional activity. The Gene 1.0 ST Arrays also complement the company’s previously launched GeneChip Exon 1.0 ST Arrays, which offer both gene-level expression profiling and alternative splicing analysis in a single experiment.
 
The Mouse and Rat Gene 1.0 ST Arrays incorporate the latest available mouse and rat genome sequence information and feature a simplified design strategy, which provides one value from one probe set for each gene, the company said. Additionally, the Mouse and Rat 1.0 ST Arrays contain more than 720,000 probes that interrogate more than 27,000 well-annotated genes.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.