Skip to main content
Premium Trial:

Request an Annual Quote

Roche NimbleGen, Affymetrix

Premium
Roche NimbleGen last week launched a line of eukaryotic 4-plex NimbleChip Multiplex Arrays for human, mouse, rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Arabidopsis thaliana, Caenorhabditis elegans, and Drosophila melanogaster. Researchers can also request custom gene expression arrays in the 4-plex format for any eukaryote with a well annotated genome, the firm said.
 
The multiplex format enables users to hybridize and analyze samples in four replicate arrays on a single slide and makes use of Roche NimbleGen’s 60-mer oligonucleotide probes in combination with high density sub-arrays of 72,000 probes allowing multiple probes per gene.
 

 
Affymetrix this week launched its GeneChip Mouse and Rat Gene 1.0 ST Arrays, the second and third installments of its Gene 1.0 ST Array System.
 
According to Affy, the gene-level arrays use its Whole Transcript Sense Target Labeling Assay and enable users to view a gene's total transcriptional activity. The Gene 1.0 ST Arrays also complement the company’s previously launched GeneChip Exon 1.0 ST Arrays, which offer both gene-level expression profiling and alternative splicing analysis in a single experiment.
 
The Mouse and Rat Gene 1.0 ST Arrays incorporate the latest available mouse and rat genome sequence information and feature a simplified design strategy, which provides one value from one probe set for each gene, the company said. Additionally, the Mouse and Rat 1.0 ST Arrays contain more than 720,000 probes that interrogate more than 27,000 well-annotated genes.

The Scan

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.

Study Points to Benefits of Local Consolidative Therapy, Targeted Treatments in Cancer Care

In JCO Precision Oncology, researchers report that local consolidative therapy combined with molecularly targeted treatments could improve survival for some lung cancer patients.

Genetic Variants That Lower LDL Cholesterol Linked to Reduced Heart Disease Risk

Rare variants in two genes that lower LDL cholesterol are also associated with a decreased risk of coronary heart disease, according to a new JAMA Cardiology study.

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.