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Roche, Fluidigm Ink Deal to Co-market Access Array Platform with 454 Sequencing

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By Justin Petrone

Fluidigm and Roche 454 Life Sciences this week announced that they have entered a worldwide co-promotional agreement that pairs Fluidigm's amplicon sample-preparation platform with Roche 454's high-throughput sequencers.

The partners will market Fluidigm’s Access Array System for use in target enrichment prior to sequencing on Roche 454's GS Junior or GS FLX System.

Launched last year, Access Array enables automated processing of 48 samples against 48 amplicons, resulting in PCR products that are ready for emPCR amplification. Amplicon sample preparation can take weeks using traditional approaches, the firms noted.

In addition to sequencing library preparation using amplicon tagging, the integrated fluidic circuit-based platform supports sample capture and target enrichment and sample barcoding for multiplexed sequencing, according to South San Francisco, Calif.-based Fluidigm.

454 CEO and President Christopher McLeod said the Access Array System and GS Junior are "extremely complementary," and enable the analysis of "large numbers of sample/amplicon combinations in an affordable workflow without the need for complicated liquid handling."

A single Access Array plate on a single GS Junior System run "generates as much data as hundreds, even thousands, of 96-well plates analyzed on a capillary sequencing system," McLeod said.

Financial terms of the deal were not discussed.

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