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Members of Noah Rosenberg's lab at the University of Michigan were working on principal components analysis, genotype imputation, and other projects using the publicly available HapMap Phase 3 data set and were surprised to produce unusual experimental results — and consequently, abnormal plots — indicative of a statistical sensitivity to the presence of unreported close relatives in the cohort. Trevor Pemberton, a postdoc in the Rosenberg lab, decided to take a closer look at the data.

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Oct
23
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