Qiagen has received US Patent No. 7,074,600, "Amplification of denatured and stabilized nucleic acids." The patent claims compositions and a method for amplification of nucleic acid sequences of interest. The method involves the replication of a target sequence so that during replication the replicated strands are displaced from the target sequence. In one form of the method, the target sample is not subjected to denaturing conditions. The primers used can be hexamer primers.