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Prolinx, Enodar


Prolinx of Bothell, Wash., has released its RapXtract fluorescent cDNA purification kit. The technology underlying this kit involves superparamagnetic particles that extract contaminating fluorescent dyes. The particles are designed to bind to precursors but not products of reactions, the company said.


Enodar, a Seattle-area bioinformatics spinoff of Fred Hutchinson Cancer Research Center, has made a demo version of its GenePlus gene expression analysis software available for download at its website, The software package, developed by Lue Ping Xhao, a professor at the Hutchinson center, adapts applied multiple regression analysis for microarray data mining. This statistical tool is designed to be particularly useful for large-scale clinical studies. In multiple regression analysis, different variables such as age, gender, and smoking status are examined in relationship to the dependent variable, which is gene expression level in the case of microarrays.

The Scan

UK Team Presents Genetic, Epigenetic Sequencing Method

Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers.

DNA Biobank Developed for French Kidney Donors, Recipients

The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France.

Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut

By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site.

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.