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In Print: Last Week's Microarray Papers of Note: Aug 5, 2014

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Signatures of selection in sheep bred for resistance or susceptibility to gastrointestinal nematodes.
BMC Genomics. 2014 Jul 30;15(1):637. [Epub ahead of print]
McRae K, et al.

Divergent lines of Romney and Perendale sheep, selectively bred for high and low fecal nematode egg count, were genotyped using the Illumina Ovine SNP50 BeadChip. The resulting genome-wide SNP data were analyzed for selective sweeps on loci associated with resistance or susceptibility to gastrointestinal nematode infection. Population differentiation revealed sixteen regions, which included candidate genes involved in chitinase activity and the cytokine response. Two of the sixteen regions identified were contained within previously identified QTLs associated with nematode.


Prevalence, antibiotic resistance patterns and molecular characterization of Escherichia coli from Austrian sandpits.
Environ Pollut. 2014 Aug 1;194C:24-30. doi: 10.1016/j.envpol.2014.07.007. [Epub ahead of print]
Badura A, et al.

The authors aimed to determine the prevalence of E. coli and coliform bacteria in playground sand of all public children's sandpits in Graz, Austria, and to assess the frequency of antimicrobial resistance in E. coli. Using microarrays, E. coli isolates were tested for susceptibility to a set of antibiotics. In total, 49 percent and 98 percent sandpits were positive for E. coli and coliform bacteria, respectively.


Development of a multiplex Luminex assay for detecting swine antibodies to structural and nonstructural proteins of foot-and-mouth disease virus in Taiwan.
J Microbiol Immunol Infect. 2014 Jul 26. [Epub ahead of print]
Chen T, et al.

The aim of this study was to develop a multianalyte profiling xMAP Luminex assay for the differential detection of antibodies to the foot-and-mouth disease virus of structural proteins and nonstructural proteins. The results indicated that xMAP has the potential to detect antibodies to FMDV-SP-VP1 and NSP-3ABC and to distinguish FMDV-infected pigs from pigs infected with the swine vesicular disease virus.

The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.