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In Print: Last Week's Microarray Papers of Note: Jun 3, 2014

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Microarray-based resonance light scattering assay for detecting DNA methylation and human DNA methyltransferase simultaneously with high sensitivity.
Analyst. 2014 Jun 2. [Epub ahead of print]

Ma L, et al.

The authors developed a microarray-based resonance light scattering assay that relies on a combination of methylation-sensitive endonuclease and gold nanoparticle probes to sensitively distinguish DNA methylation levels and to detect human DNA methyltransferase 1.


Recombination locations and rates in beef cattle assessed from parent-offspring pairs.
Genet Sel Evol. 2014 May 29;46(1):34. [Epub ahead of print]
Weng Z, et al.

The authors used the Illumina BovineSNP50 BeadChip to investigate the influence of recombination on haplotype phasing, locate recombination hotspots, scan the genome for quantitative trait loci and identify candidate genes that influence recombination, and quantify the impact of recombination on the accuracy of genotype imputation in beef cattle.


A multiplex high-throughput gene expression assay to simultaneously detect disease and functional markers in induced pluripotent stem cell-derived retinal pigment epithelium.
Stem Cells Transl Med. 2014 May 29. [Epub ahead of print]
Ferrer M, et al.

The authors developed a multiplex high-throughput gene expression assay that simultaneously detects endogenous expression of multiple developmental, functional, and disease markers in iPS cell-derived retinal pigment epithelium and optimized protocols to differentiate iPS cell-derived RPE that was then grown in 96- and 384-well plates.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.