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In Print: Last Week's Microarray Papers of Note: May 6, 2014


Comparative transcriptome analysis of aerial and subterranean pods development provides insights into seed abortion in peanut.
Plant Mol Biol. 2014 May 5. [Epub ahead of print]
Zhu W, et al.

A comparative transcriptome analysis between aerial and subterranean pods at different developmental stages was produced using a customized NimbleGen microarray representing 36,158 unigenes. By comparing 4 consecutive time-points, a total of 6,203 differentially expressed genes, 4,732 stage-specific expressed genes, and 2,401 specific expressed genes only in aerial or subterranean pods were identified.

New molecular diagnostic kit to assess Y-chromosome deletions in the Japanese population.
Int J Urol. 2014 Apr 29. [Epub ahead of print]
Iijima M, et al.

Deletions in the azoospermia factor regions are the most commonly known molecular genetic cause of human male infertility involving spermatogenetic failure. Testing for these deletions in Japanese DNA samples using conventional sequence-tagged site probes occasionally leads to considerable non-specific or faint products in the Japanese population. The authors developed a Luminex suspension array assay that they claim offers good sensitivity and specificity with time and cost savings.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.