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In Print: Last Week's Microarray Papers of Note: Nov 5, 2013


Genetic ancestry and risk of mortality among US Latinas with breast cancer.
Cancer Res. 2013 Oct 31. [Epub ahead of print]
Fejerman L, et al.

The authors evaluated the association between genetic ancestry and survival after breast cancer diagnosis among 899 Latina women from the San Francisco Bay Area. Genetic ancestry was estimated using an Affymetrix 6.0 array. Their results showed that Individuals with higher Indigenous American ancestry had increased risk of breast cancer-specific mortality.

Pneumococcal bacterial load colonization as a marker of mixed infection in children with alveolar community-acquired pneumonia and respiratory syncytial virus or rhinovirus infection.
Pediatr Infect Dis J. 2013 Nov;32(11):1199-204.
Esposito S, et al.

The authors evaluated whether nasopharyngeal Streptococcus pneumoniae colonization in children with alveolar community-acquired pneumonia and respiratory syncytial virus or rhinovirus infection indicates a mixed lung infection. The nasopharyngeal secretions of 530 children were tested using the Luminex x TAG respiratory virus panel fast assay. They determined that in children with alveolar CAP and RSV or RV infection, the determination of nasopharyngeal pneumococcal bacterial load and identification of the serotypes can contribute to the diagnosis of mixed lung infection.

A genome-wide association study of third molar agenesis in Japanese and Korean populations.
J Hum Genet. 2013 Oct 31. [Epub ahead of print]
Haga S, et al.

This study aimed to identify susceptibility genes associated with third molar agenesis. The authors conducted a genome-wide association study of 149 cases with at least one-third molar agenesis and 338 controls from Japan and Korea using the Illumina HumanOmniExpress BeadChip. They identified three SNPs showing evidence of association.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.