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In Print: Last Week's Microarray Papers of Note: Oct 1, 2013


Large-scale genotyping identifies a new locus at 22q13.2 associated with female breast size.

J Med Genet. 2013 Oct;50(10):666-73.

Li J, et al.

To identify common variants that are associated with breast size, the authors conducted a large-scale genotyping association meta-analysis in 7,169 women of European descent across three independent sample collections with digital or screen film mammograms. The samples were genotyped on iCOGS, a custom Illumina iSelect genotyping array. In addition to replicating previous findings, they identified a locus at 22q13 that may be associated with female breast size

Determination of tear and serum inflammatory cytokines in patients with rosacea using multiplex bead technology.

Ocul Immunol Inflamm. 2013 Oct;21(5):351-9.

Topcu-Yilmaz P, et al.

The authors used Luminex bead array technology to compare serum and tear inflammatory and anti-inflammatory cytokine levels of rosacea patients with the healthy controls and to evaluate the correlation of tear cytokine levels with tear function parameters.

Organic trace mineral levels in the first 96-h post-hatch impact growth performance and intestinal gene expression in broiler chicks.

Biol Trace Elem Res. 2013 Sep 28. [Epub ahead of print]

Brennan K, et al.

The objective of this study was to determine the effect of post-hatch dietary mineral supplementation on performance, tissue mineral content, and intestinal gene expression profiles in 21-day-old broiler chicks. Intestinal gene expression profiling was examined using the Affymetrix GeneChip chicken genome array. The authors found that diets fed for the 96-hour, post-hatch had long-term effects on gene expression.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.