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In Print: Last Week's Microarray Papers of Note: Aug 13, 2013


Targeted resequencing of HIV variants by microarray thermodynamics.
Nucleic Acids Res. 2013 Aug 8. [Epub ahead of print]
Hadiwikarta W, et al.

The authors used DNA microarrays and inputs from hybridization thermodynamics to resequence genomic subsets of HIV. Seven coded clinical samples were analyzed, and the microarray results were found to be concordant with Sanger sequencing data.

Surface engineering for long-term culturing of mesenchymal stem cell microarrays.
Biomacromolecules. 2013 Aug 12;14(8):2675-83.
Rasi Ghaemi S, et al.

The authors describe surface modifications to passivate cell microarrays, in order to adapt the platform to study stem cell behavior over long-term culture periods. The functionalization of glass slides with (3-glycidyloxypropyl) trimethoxysilane enabled covalent anchoring of extracellular matrix proteins on microscale spots printed by a robotic contact printer.

Automated regenerable microarray-based immunoassay for rapid parallel quantification of mycotoxins in cereals.
Anal Bioanal Chem. 2013 Aug;405(20):6405-15.
Oswald S, et al.

This paper describes the development of an automated flow-through multi-mycotoxin immunoassay based on the Munich Chip Reader 3 platform. Using the array, the authors were able to detect in parallel aflatoxins, ochratoxin A, deoxynivalenol, and fumonisins in cereal samples in a competitive indirect immunoassay format.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.